As seen in the left microscopic image of myocardium,
cells are arranged with a certain regularity. Therefore, we may define a
micro-unit consisting of a number of cells, and regard local myocardium
as a repetition of such a micro-unit. The mechanical characteristics of
myocardium can then be directly expressed by the finite element virtual
cells. With this model we can use the homogenization method, a powerful
tool to link the intra-cellular microstructure to the dynamics of the heart.
However, the homogenization method has not been applied to practical problems
because the computational cost increases explosively in nonlinear problems.
We are doing further research to overcome this problem.
Introduction of Research
Computational Science 3/4
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