| Outline of Heart Simulator | Research Subjects | Simulation of Diseases and Development of New Therapies |
| Development of Therapeutic Devices | Experiments on Cells and Virtual Cells | Experimental Validation | Computational Science | etc. |

Introduction of Research
Computational Science 2/4

The heart simulator must deal with the fluid-structure interaction problem, in which the dynamics of blood flow (governed by the Navier-Stokes equations) and viscoelastic materials (such as myocardium and valves) affect each other. From the continuum mechanics point of view, there is no distinction between fluids and viscoelastic materials, as both are governed by mass and momentum conservation laws. However, their dynamics are totally different due to the differences in constitutive laws (stress-strain-strain rate relations), which makes the fluid-structure interaction analysis difficult. To overcome this difficulty we adopt different approaches for the interaction between ventricle/atrium and blood and between valves and blood.

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